After Boone's escape, Blackfish gathered a force of about 450 Native Americans and a small group of allied white men to siege the settlement. The settlement tried to reach negotiations with the indians, but were ultimately unsuccessful, and soon gunfire began to erupt from both sides, although it is unclear which side fired first. Gunfire was exchanged over several days, and Boone, who was mistrusted upon his return over rumors of him becoming loyal to Britain began to spread after the settlers learned he willingly surrendered to the Shawnee, began to assume the role of leader once again, and urged the settlers to conserve their gunpowder. The Shawnee launched their final assault on September 17, trying to set fire to the fort, but they were soon forced to retreat. The settlers only suffered two fatalities in the siege.
After the siege, charges were brought against Daniel Boone, claiming that he was in favour of the British Government, after Boone had willingly surrendered to the Shawnee in order to save the lives of his men. The court later found Boone not guilty and was made a major due to his heroic actions. Despite being cleared of the charges, the experience was still a humiliating one for Boone, who spoke little of the incident since.