Wilkerson had his doubters; people questioned who would want to attend church services in one of the city's most crime-infested neighborhoods. But the church flourished immediately, drawing in many sex workers and addicts who occupied Times Square but hoped for a better life. The church meetings regularly included a mix of people who worked in Times Square including area office workers, local families, and tourists.
The church, which is interdenominational, is based in the charismatic tradition, meaning its members believe in healing and prophecies. Wilkerson would regularly summon to the altar anyone who struggled with addiction, depression, or suicidal impulses, for prayers of healing. Services at the church usually lasted two and a half hours, with much of the service devoted to singing and music performed by a jazz and gospel choir which has become famous in its own right.
Wilkerson died in an automobile accident in 2011, but the church he founded continues to grow. Today, the Times Square Church has five pastors, including senior pastor Carter Conlon,who joined the church's ministry at the request of Wilkerson. The church remains committed to serving society's most vulnerable and sponsors a number of missions throughout the world.