Numerous businesses have been located in the Everett Building including a drug store, barber shop, art gallery, clothing store, and even the American Red Cross during World War II. Doctors, dentists, and lawyers have also operated practices here. The building stood essentially vacant from 1960 until 1979, when the Gregg County Historical Foundation purchased it. After renovations were completed the foundation opened the museum in 1984. The building was added to the National Register of Historic Places 1979.