The DeWints hosted George Washington on several occasions, and Washington used the house as his headquarters on some of those visits. The first time Washington stayed at the home was in August of 1780, when he was inspecting a redoubt on the Hudson River. Washington again stayed in the home in September and October of that year when he returned to Tarrytown for the trial of British spy, Major John Andre.
In May of 1783, Washington used the DeWint house as his headquarters while he negotiated the final withdrawal of British soldiers from New York City. Later in the year, in November, a strong snowstorm forced Washington to stay at the home again while on his way to New York City to give his resignation.
The home was added to the National Register of Historic Places in 1966. Since that time, the DeWint home has been extensively restored, particularly its kitchen, which now appears virtually the way it would have when Washington was a guest there. The Washington Room in the house is a National Masonic Historic Site.