In 1940, the building became the Rochester Hotel and offered rooms on a daily, weekly, or monthly basis. During the first half of the twentieth century, there were a host of similar buildings in the area, as land prices were expensive and most African American residents of the district could only afford to rent rooms or apartments in larger residential complexes. While leading Black figures in the city exhorted renters to stop renting and start buying, very few African Americans could afford to do so. Indeed, most complexes like the Western Apartments/Rochester Hotel were owned by white people; in 1913, just before the apartments were built, only 3.4 percent of Black residents of Kansas City owned property. The pressing need for housing, the poverty of many African Americans, and the segregated urban landscape combined to create poor living conditions in many of the housing options accessible to lower- and working-class African Americans. 
Hotels like the Rochester were some of the few places that visiting African Americans—like the jazz musicians and baseball players for which the historic district is so well known—could stay, and the movement of artists and athletes through residential spaces influenced the surrounding area profoundly. Next door to the Rochester is the Mutual Musicians' Foundation building, which was originally purchased the Musicians Local Union 627 in 1928 to serve as the union headquarters. Local 627 benefited tremendously from the influx of visiting musicians, some of whom ended up sticking around Kansas City, especially during the Great Depression.  While the Rochester catered to a working class population, other hotels in the area like the now-razed Street Hotel were more luxurious and combined residential, dining, and entertainment options under one roof. The famous Blue Room, celebrated by a replica connected to the American Jazz Museum, was part of Street's.
Many of the large residential complexes like the Rochester and Street's were razed as part of urban renewal projects after World War II. The Rochester building is one of the largest surviving residential buildings from this period, though it no longer functions as a hotel. Once again, the building contains apartments, with recent property records indicating that there are 8 units in the building—significantly fewer than the 24 that existed during the days of the Western Apartments.