Among the noteworthy graves in the cemetery is a mass plot devoted to the cholera outbreak of 1850. The plot holds the remains of approximately 600 victims of the epidemic. John Sutter, Jr., founder of Sacramento, is also buried in the cemetery. Numerous other state politicians and Supreme Court justices are buried there as well.
In addition to its well-known residents, the cemetery is also known for its roses. The rose garden was established in 1992, with approximately two percent of the garden made up of species from the Victorian era. The cemetery's roses are considered to be some of the finest in California.
The cemetery was declared a State Historic Landmark in 1957 and was added to the National Register of Historic Places in 2014.