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Twining Laboratories was founded in 1898 by Frederick Twining. The building itself was designed by Charles E. Butner in a style with Mediterranean influences. The building is listed on the National Register of Historic Places.


  • Twining Laboratories

Frederick E. Twining came to Fresno in 1898 and established Cutter Laboratories. For a number of years following the lab's establishment, Twining served as State Sanitary Inspector as well as the City Bacteriologist for Fresno. In 1913, he established Twining Laboratories, which quickly earned a reputation throughout the state for its scientific work.

With its slogan "We Test Anything," Twining Laboratories became a leader in scientific investigations. The laboratory was involved in vaccine testing for cattle, sobriety testing, and food and drug testing. Following Twining's death in 1945, his son, Frederick W. Twining, himself a respected chemist, assumed leadership of the company.

The building was designed by Charles E. Butner, a well-known architect in the area. Butner designed the building with Mediterranean elements. The style was relatively common during the Depression era for schools and residences, but less common for businesses. The building is listed on the National Register of Historic Places. 

Twining Laboratories. A Guide to Historic Architecture in Fresno, California. Accessed July 29, 2017. http://historicfresno.org/nrhp/twining.htm.