Church Street was perhaps intended to serve as Blacksburg's main street. This road terminates in T-intersections on either end. Like other T-intersections in Blacksburg, buildings are situated at the end of those on Church Street. At the intersection between Church and Jackson is the Old Town Hall. The intersection between Church and Clay Street is the site of the old Blacksburg Middle School. In the 1800s, Church Street would have been the location of a mixture of residences, hotels, stores, and student housing. Points of interest along Church Street include Christ Episcopal Church (built 1875-79) and the Blacksburg United Methodist Church (built 1906).
Since its establishment in 1798, Blacksburg has grown well beyond its original limits. The original town of Blacksburg occupied sixteen square blocks, each made up of four lots. These lots are bounded by Jackson Street on the northwest side, Wharton Street on the northeast, Draper Road on the southwest, and Clay Street on the southeast. Within the square are several main thoroughfares including Main Street, Church Street, Roanoke, and Lee. Many of the streets terminate in T-intersections (nine in total), which help give an idea of the limits of the original town.