Edward Ripoll, the original owner of Bud Rip's Bar in New Orleans and a Republican member of the Louisiana House of Representatives from 1984 to 1988, organized a golf tournament in the 1980s to help with repairs to St. Vincent de Paul and to assist surviving families of police officers killed in the line of duty.
In 2001, as part of a study of parish facilities, the Roman Catholic Archdiocese of New Orleans announced that five parishes in the area would be merged into one parish. Annunciation, St. Cecilia, St. Gerard (a parish for the hearing-impaired), Sts. Peter and Paul, and St. Vincent De Paul were merged into a new parish, Blessed Francis Xavier Seelos. The new church was located in the church and facilities of St. Vincent De Paul. On May 25, 2003, the building was severely damaged by a fire. The main altar was destroyed, along with several murals and the sacristy. As part of the repairs, the former altar from Sts. Peter and Paul Church was moved to Blessed Seelos Parish, along with the pulpit from St. Cecilia. Hurricanes Katrina and Rita caused further damage to the nearby St. Gerard Center (the former Motherhouse of the Sisters of the Immaculate Conception), forcing the church to replace the roof.