Mary Flannery O'Connor was the only child of Regina Cline and Edward F. O'Connor, a product of the marriage of devout Roman Catholic Families in the Savannah area. Her father was stricken with lupus and the family decided to move to Millidgeville, Georgia for his health3. O'Connor's father passed away in 1941 and she was invited to attend the prestigious Iowa Writers Work (University of Iowa) for her graduate degree in creative writing3. She would go on to write some of the most prolific works of the Southern Gothic Literary Movement, starting with her novel Wise Blood in 1952. O'Connor is also known for her short stories and essays. Her collection A Good Man is Hard and Other Stories is considered the catalyst for her literary career. O'Connor would face the same disease as her father, systematic lupus erythematosus, after she had an attack in 1950 and would move to her mother's ancestral farm permanently, quietly living at Andalusia until her death in 19644. Her posthumous collection, The Complete Stories won the National Book Award in 1972 and three O. Henry Awards for short stories3.
In 1989, The Flannery O'Connor Childhood Home Foundation purchased the house. In 2006-2007, the home went through a major $100,000 renovation, the majority funded by Jerry and Linda Bruckheimer, and the Bruckheimer Library inside the home that features Flannery O'Connor's work and childhood books, as well as books from the Great Depression period2. The museum hosts events like The Peacock Party, Ursrey Lecture Series, and the free Sunday lecture series.