Exhibits in the museum include many different galleries telling the stories of the civil war times. Some of which include First Shots at Fort Sumter in 1861, Camp Curtin, the civil war's largest Union camp, and Campaigns and Battles from the beginning and endings of the civil war. There are exhibits that focus on other aspects of life during the war. These including Women in the War, which focuses on the roles of women during this time, American Slavery, focuses on how people viewed slavery at this time, and Costs of Civil War, which shows the costs of war medicine and other things. The museum also recently added an exhibit that utilizes touch-screen technology that permits patrons to virtually interview historic figures such as Abraham Lincoln, Mary Todd Lincoln and John Wilkes Booth.
There is a large collection of artifacts at the National Civil War Museum. These artifacts include weapons, uniforms, ect from war time. While all artifacts are interesting, some include the carbine and pike head from the raid on Harper's Ferry in 1852, Lincoln's hat box used in his first term in 1860, and Major General George McClellan's saddle used in the Union army. Other artifacts include more personal items of the veterans of war, including a lock of hair from General George Pickett, chains and shackles from the slave trades, and a gauntlet worn by Stonewall Jackson.