The museum has exhibits on several different aspects of Tampa's baseball history, such as the Little, Major, Factory, Inter-Social, Municipal, Cigar City, and Negro Leagues. It is run by the Ybor City Museum Society. The Ybor City Museum is right across the street too, so visitors can walk from one museum to the other.
The location for the house-museum is not the original location where Al Lopez resided. The original location was 1210 E. 12th Ave. For purposes of parking, the house was moved to its current location. Work on the museum began just a few years ago and not opening date has been announced as of yet.