Unfortunately, in addition to losing his daughter and two grandchildren, McMurran's wealth dwindled due to the aftermath of the Civil War, and he was forced to sell his mansion and land.
Elizabeth Davis purchased the estate in 1865. However, Davis and her attorney husband rarely occupied the estate and Melrose stood mostly vacant for forty years. The home eventually was passed to George Malin Davis, who was only six years old at the time he became the legal owner of the home. He moved to New York where he was raised by his grandmother, but upon marrying in 1900, returned to Melrose to live. The Davis family remained in the home for 75 years until Mrs. Davis's death.
The home was then purchased by John and Betty Callon, owners of the well-known oil company Callon Petroleum Company, in 1976. The couple restored the home, preserving its original antebellum flair. Unfortunately, when their petroleum business suffered economically, they were forced to sell Melrose.
In 1990, Melrose was bought by the National Park System and is now a part of the Natchez National Historic Park.