Even after the war ended, the Greens leased the mansion to the State, and it was used as a recovery home for wounded soldiers. The Greens finally moved back into their home in 1866 and lived there until 1880 when Mr. Green passed away and Mrs. Green sold the mansion to the Peatross family, who lived there until 1910. Then, the home was purchased by Fannie Vick Willis Johnston, a great-granddaughter of Vicksburg’s founder Rev. Newitt Vick.
In 1913, Mrs. Johnston donated the home as an orphanage for boys. And later, it served as a retirement home for the elderly. After Mrs. Johnston's death in 1931, the Salvation Army purchased the mansion and used it as their headquarters until 1985 when they relocated to a larger property. Mr. & Mrs. Harry Carter Sharp purchased the home, and according to the Duff Green Mansion's official website,
The Sharps completely restored the Mansion to her former glory over a two and one half year period with the professional expertise of local architect Skip Tuminello. The combined efforts of The U.S. Department of the Interior, The Mississippi Department of Archives and History, and Tuminello insured the accuracy of the restoration. As many as twenty-seven layers of paint were removed, thirteen fireplaces restored, and fifteen bathrooms added. Magnificent chandeliers grace the fifteen and one-half foot tall public reception rooms painted in vivid historic colors. The entire mansion is decorated with period antiques and accented with works of art.
Today, the Duff Green Mansion operates as a Bed & Breakfast.