Over its decades of operation, the depot served as important hub of activity. It was not just a train station; it was a gathering place to socialize for the community. In 1971, passenger train service ended. During the 1980s, train companies began to downsize operations which meant selling lighter used rail lines. The Chicago Northwestern Railway Company sold the 208 mile line between Green Bay and Milwaukee in 1987 to the Fox River Valley Railroad which later sold it to the Wisconsin Central Transportation Corporation. All railroad operations ended by 1994. Two years later it was renovated to house the Titletown Brewing Company, which has an upscale dining restaurant and microbrewery.
In 2003, the company bought the Receiver Statue, the sculpture depicting a Packers wide receiver catching a football, from the Packers Hall of Fame Museum and installed it outside the building. In 2013, the statue was repainted and dedicated to former Packers wide receiver, Donald Driver.