The Museum also hosts multiple rotating exhibits and special events. Exhibits focus on the cultural impact of quilting, technological advancements, and changes in quilting styles through the years. Rotating exhibits may also include contemporary quilters from both the Virginia area and around the world. Special events are frequently held throughout the year.
The Museum is located inside the Warren-Sipe House. This house was built in 1856 by Edward Tiffen Harrison Warren. During the Civil War the home was used as a makeshift overflow hospital. George E. Sipe purchased the house in 1894 and built several additions. The home has since been used as a recreation center and as a temporary courthouse. A small holding cell can still be found from this era in the home's history.