In 1926, Camac moved his office to Orange City where he invested heavily in Orange City. He built the Erwin Hotel and Laverne Apartments, gave generously to fund the construction of the new M.E. Church and owned several other properties on Volusia Avenue. Local builder J.P. Prettyman worked closely with Camac on several projects. Prettman also did the renovation and stucco work to Camac’s own house at 401 East Graves Avenue in Orange City. In 1926 Camac's investments in the city topped $300,000.
In 1926, John also help organize the Orange City Bank and served as Vice-President. The bank building at 211 North Volusia Avenue is now home to the Webster Medical Clinic. In 1927 John W. Camac made improvements to his properties and planted 500 trees on his properties
John W. Camac died on September 27, 1929 at 10:30 a.m. at a hospital in Daytona Beach. His funeral service was held on September 28, 1929 at the Baggett-Wetherby mortuary on South Beach Street, Daytona Beach. Dr. D. Stratford Scadening, pastor of the First M.E. Church of Orange City officiated. He was survived by his wife Sallie and two sisters from Philadelphia who were at his bedside at his death.