For decades, the hotel was one of the most famous in the United States. It hosted numerous Hollywood celebrities and political dignitaries, including J. P. Morgan, Katherine Hepburn, John Wayne, William Jennings Bryan, and the Vanderbilt family. The hotel has also hosted every US President since Theodore Roosevelt.
The late twentieth century would not be so kind to the Bellevue Stratford, however. In July of 1976, the hotel hosted thousands of members of the American Legion for their annual convention. When the attendees returned home, many began developing strange symptoms and complained of tiredness and chest pains. Many people feared an outbreak of swine flu or a return of the deadly flu epidemic that killed millions in 1919. After CDC investigators were brought in, it became apparent that whatever the disease was, the Bellevue Stratford was at its epicenter.
Ultimately, 182 people who stayed at the hotel in late July of that year became sick, and of those, 29 died. The culprit was eventually identified--a previously unknown bacteria that scientists named Legionella pneumophila---or Legionnaire's Disease, likely carried by the hotel's cooling system. The hotel was forced to close following weeks of plummeting reservations. The hotel was eventually sold in 1978 and completely renovated, including the installation of a new heating and cooling system.
The hotel's revitalization helped spur the revitalization of Broad Street. Today, the historic property is owned by Hyatt followed extensive renovation and modernization. The building was added to the National Register of Historic Places in 1977 and is once again considered one of the finest places to stay in Philadelphia.