In 1965, Virginia Tech purchased the building, along with the neighboring buildings that it calls the Agriculture Annex and Media Annex (formerly Blacksburg High School and Montgomery County School Board Agricultural Building, respectively), for a total of around $300,000. While other construction was taking place on campus, these buildings were vital for temporary use. From 1966 to 1969, student organizations used the building while Squires Student Center was being renovated, and eventually the campus university relations department moved its offices there. In 2017, the Center for the Arts at Virginia Tech moved into the building.
A similar institution to the historical Blacksburg Female Academy in the area was the Montgomery Collegiate Institute/Montgomery Female College, which operated in nearby Christiansburg, Virginia. The two institutions were unaffiliated.